Celexa Approval
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چکیده
DESCRIPTION Celexa (citalopram HBr) is an orally administered selective serotonin reuptake inhibitor (SSRI) TM with a chemical structure unrelated to that of other SSRI’s or of tricyclic, tetracyclic, or other available antidepressant agents. Citalopram HBr is a racemic bicyclic phthalane derivative designated (±)-1-(3-dimethylaminopropyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile, HBr with the following structural formula: [Structural formula here} The molecular formula is C H BrFN O and its molecular weight is 405.35. 20 22 2
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Celexa Approval
DESCRIPTION Celexa (citalopram HBr) is an orally administered selective serotonin reuptake inhibitor (SSRI) TM with a chemical structure unrelated to that of other SSRI’s or of tricyclic, tetracyclic, or other available antidepressant agents. Citalopram HBr is a racemic bicyclic phthalane derivative designated (±)-1-(3-dimethylaminopropyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitr...
متن کاملCelexa® (citalopram hydrobromide) Tablets Rx Only Suicidality and Antidepressant Drugs Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major
Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (MDD) and other psychiatric disorders. Anyone considering the use of Celexa or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need. Short-term...
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Results: Overall, women who took tamoxifen plus a CYP2D6 inhibitor (mean duration of concurrent treatment, 340 days) had a nearly 2-fold increase in breast cancer recurrence, compared with those who took tamoxifen alone (14% vs 7.5%; p<0.001). Concurrent users of one of the moderate/potent CYP2D6 inhibiting SSRIs (i.e., fluoxetine, paroxetine, sertraline) had the highest recurrence rate (16%). ...
متن کاملManufacturing Madness: The Pseudoscience of Modern Psychiatry
Twenty-six years have passed since Prozac, the antidepressant drug, was introduced to the US market and quickly achieved the label of a "wonder drug." In the decade that followed, other antidepressant drugs including paroxetine (Paxil), sertraline (Zoloft), fluvoxamine (Luvox), and citalopram (Celexa) would be released, creating an entire class of medications known as selective serotonin reupta...
متن کاملThe formulary files. Select SSRIs increase level of HMO drug formulary access despite generic incursion.
Generic versions of Prozac (fluoxetine) have been available to patients for approximately 18 months, and a court decision is expected this month on whether generic Paxil (paroxetine hydrochloride) may be marketed. Yet in the face of this, several SSRI brands have increased HMO drug formulary access. We analyzed 2001 and 2003 data from MediMedia’s Formulary Compass database for the HMO market. G...
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